Understanding primary hyperoxaluria type 1 (PH1)
PH1 is a genetic disease that is rare and progressive. If you have PH1, it is important to work with your doctor.
PH1 causes the body to produce too much oxalate
- Oxalate is a waste product that is mostly removed by the kidneys
- In PH1, too much oxalate is made in the body
- As excess oxalate moves through the kidneys, it can form crystals that may cause kidney stones
How PH1 can affect the body
Kidney stones are the most common symptom of PH1 Any kidney stone in a child or adolescent or recurring stones in adults can be signs of PH1.
PH1 is more than a kidney stone disease Even if someone is not experiencing kidney stones, too much oxalate can cause serious damage to their kidneys and other organs.
Too much oxalate in the body can lead to permanent damage PH1 can result in kidney failure that may require dialysis and potentially lead to a kidney transplantation. That’s why PH1 may require ongoing management and monitoring with your doctor and a well-coordinated care team.
PH1 can affect each person differently It is important to work closely with your doctor to develop a personalized management plan.